Measurement of Daytime Melatonin and Norepinephrine in Chronic Fatigue Syndrome by Bi-Digital O-Ring Test and the effects of TCM

Measurement of daytime melatonin and norepinephrine in Chronic Fatigue Syndrome by Bi-Digital O-Ring Test and the effects of TCM

Abstract

Purpose

When the auther tested patients with Chronic Fatigue Syndrome (CFS) by Bi-Digital O-Ring Test (BDORT), an infection was found in the pineal gland in all patients. Therefore to clarify the role of the pineal gland in the pathology of CFS, concentration of the melatonin (MLT) and norepinephrine (NE) were estimated using Bi-Digital O-Ring test and carefully observed the effects of Chinese herbal medicine.

Materials and Method

Four patients who met the CDC diagnosis criteria were selected. Samples of different concentrations of MLT and NE were prepared and examined the patients at points representing the pineal gland and other areas of the forehead at a specified time of the day using BDORT. Chinese herbal medicines were chosen with the help of BDORT with the aim of reducing the amounts of NE and MLT in the pineal gland

Results

The patients consisted of three women and one man, ages 16 to 78. Their length of illness ranged from three to 33 years. CMV infection and HSV II infection in the pineal gland were detected in two patients each. Evidence of viral infection was found in the hypothalamus, pituitary gland, suprarenal glands and head. The ratio of pineal gland representative points to the amount of NE found in the forehead varied among the four patients as follows : 20,000 to one after four weeks, 4,400 to two after four weeks, too-high-to-measure to ten after eight weeks and 2,500 to 33 after four weeks. The amount of melatonin in the forehead reduced with each patient : from 500 pg to 30 pg after two months, from 600 pg to 20 pg after three months, from 600 pg to 20 pg after three months, and from 800 pg to 35 pg after five months. The levels became almost normal in each case. The amount of melatonin in the pineal gland was approximately five times higher than that in the forehead. Each patient has admitted improved subjective symptoms, and is now able to go to school, go to work, and to do housework. The Minor Cinnamon and Paeonia Combination (Hsiao-chien-chung-tang) was used for three patients and the Astragalus Combination (Huang-chi-chien-chung-tang) for one patient.

Conclusions

The above indicates that continued á adrenergic nerve tension which was brought on by infection in the pineal gland hindered the daytime production of melatonin which is normally induced by photic stimulation. Disrupted melatonin circadian rhythm is considered critical in the pathology of CFS. TCM has also been extremely effective in CFS treatment.

Cognizant Communication Corporation.

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By Takayuki Aoki

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