The Cause of Heart Disease


"As a drug chemist for a leading pharmaceutical company I made a startling discovery: you do not have to be dependent on FDA approved drugs to avoid heart disease. In fact, research clearly shows the opposite. You don’t need a single prescription drug to avoid this killer. Consider this, FDA approved drugs - used as prescribed - are killing over 125,000 people every year. Nationally, this makes prescription drugs the fourth leading cause of death after cancer, heart disease, and stroke. That does not count death by hospital medical error, which adds 98,000 deaths to this atrocity. Hypnotized by drug ads, the general public is oblivious to the deaths caused by prescription drug use. This is evidenced by their willingness to swallow whatever “the doctor ordered.” This is especially true for drugs targeting heart disease. The best selling drugs of all time are the cholesterol-lowering drugs known as "statins." They procure drug makers and their shareholders billions of dollars in profits every year. The success of these drugs is not attributed to their effectiveness but instead to slick and misleading marketing practices. This hype is fueled by egregious conflicts of interest amongst drug company servants disguised as experts. Don't be surprised if your own doctor falls within this group. The truth be told, statin drugs are poisons - foreign to the human body and may at times be life threatening. Avoiding heart disease should not be expensive or dangerous. A plethora of natural alternatives exist. Understanding them as outlined in this paradigm shifting book will arm you with the understanding and courage not to accept popular dogma. It may prove to be one of the greatest assets to your health." -- Shane Ellison

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Shane Ellison is an award winning organic chemist, author and lecturer. He is a two-time recipient of the prestigious Howard Hughes Medical Institute Research Grant for his studies in biochemistry and physiology. He is also co-author with Dr. Joseph Mercola and Dr. Julian Whitaker of 101 Great Ways to Improve Your Health. Shane is a proud member of The International Network of Cholesterol Skeptics. He has been quoted by USA Today and speaks to large corporations such as BP. His monthly column is read by over 300,000 readers.


There have been careful experiments with guinea pigs, first attempted by the Canadian Willis in the mid 1950s. The result is always the same. When these animals are deprived of any vitamin C they die a terrible death in a matter of weeks. When their vitamin C is limited to the U. S. RDA they live, but develop atherosclerosis. When they are fed roughly the human equivalent of 3 to 5 gm of vitamin C, they thrive with no signs of atherosclerosis.

Disease in guinea pigs occurs in weeks, the human form of the disease usually takes decades to develop. While differences are to be expected in animal experiments, the lesions produced by these experiments are remarkable for their similarity to the human lesion. The Pauling/Rath vitamin C theory you are about to learn about makes sense. Animals, other than guinea pigs, manufacture their own vitamin C in the amount of several thousand milligrams every day. Humans, like guinea pigs and other primates, can not make a single molecule of vitamin C in their bodies.

During the 1970s vitamin C consumption in the U.S. rose by 300%. Mortality from heart disease decreased by 30% in the U.S. ­ the only country with a significant drop in heart disease fatalities. Yet, the media and organized medicine ignore these facts and disseminate misrepresentations of scientific findings regarding the value of vitamin C. Under the heading truth is stranger than fiction, a recent media campaign credits a substance found in "junk food" for what they claim is a 40% reduction in heart disease mortality during the past 2 decades in the United States.


Science has known for almost two decades that damage to the walls of blood vessels (or lesions) are a necessary precondition for the formation of atherosclerotic plaques in human beings. The most popular competing theories why these lesions occur include:

1. Oxidized cholesterol in the blood,
2. Elevated levels and oxidized homocysteine in the blood, and
2. Vitamin deficiencies.

( We think it is safe to say that not many researchers believe that high levels of fat or cholesterol in the diet are the primary cause of heart disease. An exception may be researchers working for companies that offer high priced cholesterol lowering medications. )

In our view, all competing theories must be able to explain:

1. Why occlusive cardiovascular disease does not occur in animals, and
2. Why infarctions in humans usually occur in the arteries at locations where the mechanical stress (blood pressure, arterial bending and stretching, etc.) is a factor, rather than more randomly distributed throughout the body.

These two observations are the cornerstones of the vitamin C theory.

Furthermore, the early findings of Canadian doctors Patterson and Willis should not be forgotten. Their research indicated that arterial tissue levels of ascorbate (vitamin C) are much lower in heart patients when compared with controls, and that ascorbate supplementation could reduce arterial deposits. This pioneering work should have been immediately followed up.

During the last decade, 2­time Nobel Prize winner Pauling and his associate and heart researcher Dr. Matthias Rath, M.D., building on the work of Patterson and Willis, independently formulated their own assessment regarding the cause and nature of occlusive heart disease. They agree that heart disease is essentially a natural repair process that is started by a lesion; their theory explains the primary reason these lesions occur. Accordingly, what we call atherosclerosis, or human cardiovascular disease, is a natural body healing process for the walls of arteries and veins structurally weak from insufficient collagen, a condition caused by inadequate vitamin C in the diet.

The oxidized cholesterol and homocysteine theorists, while pointing to their own experiments, have yet to satisfactorily explain the distribution of infarctions. They are usually close to the heart. Nor do these theories explain why animals that produce their own vitamin C in large amounts are free from the same disease.

There is a strange omission of information about vitamin C in the medical textbooks. (This assertion is easily verified.) The result is that most medical practitioners today are grossly ignorant of the properties of ascorbic acid and find it difficult to believe that ascorbic acid deficiency could be the root cause of heart disease.

There is evidence that textbooks earlier this century contained much more information about vitamin C. Most certainly the information about vitamin C and collagen production was there. Why the change? Shouldn't we have learned even more by now? If Pauling was correct about vitamin C, then it is likely the mysterious missing info about vitamin C is an intentional omission and constitutes scientific fraud.
If you are a medical student, ask your professors why so little information is provided about one of the most important vital substances known. [Owen Fonorow]

According to Stephen Jeffrey, DDS, private correspondence:

"The ongoing effort to discredit vitamin C began in the 1940s after it was shown to have anti viral and antitoxic properties. Certain members of the pharmaceutical­medical complex, after first promoting vitamin C as a treatment for fevers and infections, realized that widespread use of this non prescription substance would cancel the need for developing a lucrative prescription anti viral drug market.

For this reason, all the scientific trials which have not shown vitamin C to be of any benefit against viral attacks either shorted the recommended dose or altered the recommended treatment procedure. Anyone who knows the vitamin C has been blatantly discredited in this manner should be ashamed to speak of ethics in order to forestall a proper evaluation of the vitamin's therapeutic potential. [Referring to the recent NY Times story]

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