Aspartame Linked to Diabetes


Below are References that Link Aspartame to Diabetes

This continues the last post so it won't be so long. Here are some of the references and citations from an article about independent testing on aspartame by Barbara Mullarkey, the journalist who has been writing about aspartame since its approve. The article was titled NEUROTOXIC POTENTIAL OF ASPARTAME. At a later date we will probably scan it in.

1. Stegink, L.: Filer, L.J. Jr. Aspartame Physiology and Biochemistry.
University of Iowa College of Medicine. Iowa City, IA Marcel Dekker,
Inc. 1984.

2. Camfield, P.R.: Camfield, J.M.: Dooley, J.M.: et al with generalized
absence epilepsy: A double-blind controlled study. Neurology (42) 1000-1003
(May 1992)

3. Boehm, M.: Bada, J. Racemization of aspartic acid and phenylalanine
in the sweetener aspartame at 100 degrees C. Proc. Natl. Acad. Sci. USA
(81) August 1984.

4. Walton, R. G. "Seizure and mania after high intake of aspartame."
Psychopathology 17:98-106 (1984)
5. Drake, M.E. "Panic Attacks and Excessive Aspartame Ingestion." The
Lancet (Sept 13, l986) p. 631

6. Walton, R. G. "The Possible Role of Aspartame in Seizure Induction"
Proceedings of the First International Meeting on Dietary Phenylalanine
and Brain Function. (May 8-10 1987) pp.495-499

7. Epstein, C. M.: Trotter, J.F.: et al "EEG Mean Frequencies are
Sensitive indices of Phenylalanine Effects on Normal Brain."
Electroencephalography and Clinical Neurophysiology 72:133-139 (1989)
8. Pinto, J.M.B." Maher, T. J. "Administration of Aspartame Potentiates
Pentlyeneterazole and Fluorothyl-Induced Seizure in Mice."
Neuropharmacology 27 (1):51-55 (l988)

9. Olney, John "Excitatory Neurotoxins as Food Additives: An Evaluation
of Risk." Neurotoxicology 2:163-192 (1980)

10. Koehler S.M.: Glaros, A. "The effect of aspartame on migraine
headache." Headache 28:000-000 (l988)

11. Edmeada, J. Editorial: "Aspartame and Headache." Headache, pp.64-65
(February, 1988)

12. Lipton, R. B.; Newman, L. C.: Solomon, S. "Aspartame and headache,
(re:Schiffman et al study)," New England Journal of Medicine 318 (18):
1200-1201 (May 5, 1988)

13. Steinmetzer, R.V.: Kunkel, R.S. "Aspartame and Headache" New England
Journal of Medicine 318 (18): 1201 (May 5, 1988)

14. Koehler, Shirley; and Glaros, Alan. "The Effect of Aspartame on
Migraine Headache." Headache 28 (1):10-14 (l988)

15. Olney, J. W.; and Ho, Ol. "Brain damage in Infant Mice Following
Oral Intake of Glutamate, Aspartate or Cysteine." Nature 227:609-611
(August 8, 1970)

16. Olney, J. W. "Excitotoxic Food Additives - Relevance of Animal
Studies to Human Safety." Neurological Behavioral Toxicology and
Teratology 6:455-462 (l984).

17. Olney, J. W.; Labruyere, J: DeGubaret, T. "Brain Damage in Mice from
Voluntary Ingestion of Glutamate and Aspartame." Neurobehavioral
Toxicology 2:125-129 (l980)

18. Roberts, H. J. "Does Aspartame Cause Human Brain cancer?" Journal of
Advances in Medicine 4 (4): 231-241 (Winter, 1991).

19. Potenza, D." El-Mailakh, Rif S. "Aspartame: Clinical Update."
Connecticut Medical Journal 53 (7): 395-400 (l989)

20. Sardesai, V.M.: Holliday, J.F.; et al. "Effect of Aspartame in Normal
and Diabetic Rats." Biochemical Archives 2:237-243 (l986)

21. Federal Register 48:54993-54995 (Dec 8, l983)

22. Yokigoshi, H.: Roberts, C. F>: Caballero, B.: Wurtman, R. J.
"Effects of Aspartame and Glucose Administration on Brain and Plasma
Levels of Large Neutral Amino Acids and Brain 5-Hydroxyindoles." American
Journal of Clinical Nutrition. 40:1-7 (July 1, 1984)

23. Krause, W.:Halminksi, M." et al. "Biochemical and Neuropsychological
Effects of Elevated Plasma Phenylalanine in Patients with Treated
Phenylketonuria." Journal of Clinical Investigation 75: 40-48 (January,

24. Pardridge, W.M. "Potential Effects of the Dipeptide Sweetener
Aspartame on the Brain. Nutrition and the Brain 7:199-241 (l986)

25. Gaines, S. M.: Bada, J.I. "Reversed Phase, High-Performance Liquid
Chromatographic Separation of Aspartame Diastereomeric Decomposition
Products." Journal of Chromatography. 389-:219-225 (l987)

26. Filer, L. J.; Stegnink. L.D. "Effect of Aspartame on Plasma
Phenylalanine Concentration in Humans." Proceedings of the First
International Meeting on Dietary Phenylalanine and the Brain Function
(May 8-10, l987) pp 25-26

27. Matalon, R.: Michals, K.:et al. "Aspartame Consumption in Normal
Individuals and Carriers for Phenylketonuria (PKU)." Proceedings of the
First International Meeting on Dietary Phenylalanine and Brain Function
(May 8-10, l987) pp. 81-93

28. Matalon, R. Michals, K." Sullivan, D.; et al. "Aspartame Consumption
in Normal Individuals and Carriers for Phenylketonuria (PKU)." University
of Illinois at Chicago, Department of Pediatrics, Nutrition and Medical
Dietetics and Epidemiology and Biometry, Chicago, Illinois (l986).

29. Tocci, P.M.: Beber, B. "Anomalous Phenylalanine Loading Responses in
Relation to Cleft Lip and Cleft Palate." Pediatrics 52: 109-113 (July l973)

30. Steilman, S.D.:Garfinkel, L. "Artificial Sweetener and One Year
Weight Change Among Women." Preventative Medicine 15:195-202 (l986)

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