Cholesterol-lowering effect of soy protein

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Cholesterol-lowering effect of soy protein

Cardiovascular heart disease is a major health problem in the United States. Elevated blood cholesterol has been shown to significantly increase the risk of cardiovascular heart disease. Soy protein has been shown to lower cholesterol, particularly in those with high cholesterol. It has been shown that dietary soy protein, compared with casein (principal protein of milk), reduces blood LDL cholesterol and increases HDL cholesterol concentrations in healthy women and men. Soy protein has been shown to lower cholesterol, particularly in those with high cholesterol. Thirteen men aged 20-50 with normal cholesterol and 13 with high cholesterol men were fed either a soy-protein diet or the animal protein diet for 5 weeks. After 1 month of consuming each diet, HDL cholesterol concentrations were increased by the soy-protein diet. In 5 individuals, soy protein reduced mean LDL cholesterol concentrations by 26%, whereas HDL cholesterol increased by 11%. In 3 other individuals, soy protei n increased mean HDL cholesterol by 17%, but did not lower LDL.

The cholesterol lowering effect of soy protein was found to be independent of age, body weight, pretreatment blood fat concentrations, and sequence of dietary treatment. The researchers identified 3 types of responses from excess lipids in the blood to that of dietary soy protein, which all involved a reduction in atherogenic LDL and increase in antiatherogenic HDL. The results indicated that soy protein enhances the cholesterol lowering effect in men with both normal and high cholesterol.

American Journal of Clinical Nutrition, 1998, Vol 68, Iss 6, Suppl. S, pp 1380S-1384S

Life Extension Foundation.

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