Let's take a look at history and polio!
Dylan Garner
1824: Metal workers had suffered for centuries from a paralysis similar to polio caused by the lead and arsenic in the metals they were working with. English scientist John Cooke observed: 'The fumes from these metals, or the receptance of them in solution into the stomach, often causes paralysis.'
1890: Lead arsenate pesticide started to be sprayed in the US up to 12 times every summer to kill codling moth on apple crops.