Nerve growth factor and norepinephrine regulate galanin expression in primary cultures of dorsal root ganglion neurons


Nerve growth factor (NGF) is one of the well characterized regulators of galanin expression. NGF deprivation can induce galanin expression in dorsal root ganglion (DRG) neurons. Galanin is recogn...

Are you addicted to fat?


Sure, we all are, say scientists who think they may have found a way to switch off your fat tooth.

CHOCOLATE ICE CREAM slowly melting under a glaze of hot fudge. Heavily marbled prime rib, tender at the center, crisply roasted at the edges. Or the good old American standby, a cheeseburger and fries. Name your weakness.

We all have one when it comes to high-fat fare, and most of us can't help caving in to our cravings-even when we're convinced that a low-fat diet will make us feel better, look better, and live longer.

Fat cravings may all be in your hand


Researchers have discovered two naturally occurring brain proteins, one that increases the craving for fatty food and one that blocks it. Sarah Leibowitz at New York's Rockefeller University identified galanin, which triggers a craving for fat in rats. When blocked, dramatic weight loss is achieved. David York of Louisiana State University identified enterostatin, which when injected into animals, decreases fat craving, cutting fat intake by 50 to 80%.

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